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Also known as
generalized lymphatic anomaly/lymphangiomatosis
is a

Complex lymphatic anomalies (CLA)

Complex lymphatic anomalies (CLA) consist of the four related conditions that are caused by gene mutations resulting in malfunctions in the body’s lymphatic system. CLAs are chronic and debilitating conditions that can be fatal. These conditions can affect children and adults. Treatments for CLA can vary from patient to patient, and most are aimed at easing symptoms.

Generalized lymphatic anomaly (GLA or Lymphangiomatosis)

Generalized lymphatic anomaly (GLA or Lymphangiomatosis) is one of the four conditions that falls under CLA. It most commonly involves fluid leakage in the chest, heart, abdomen, or other organs, resulting in pain and breathing problems.

The latest on our research

We are jumpstarting our GLA program in partnership with the Lymphangiomatosis & Gorham’s Disease Alliance to accelerate research for the condition. We welcome all patients, caregivers and researchers interested in participating and spreading the word to the GLA community.

Information about

GLA (lymphangiomatosis)



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