Complex lymphatic anomalies (CLA)

Complex lymphatic anomalies (CLA) consist of the four related conditions that are caused by gene mutations resulting in malfunctions in the body’s lymphatic system. CLAs are chronic and debilitating conditions that can be fatal. These conditions can affect children and adults. Treatments for CLA can vary from patient to patient, and most are aimed at easing symptoms.

Gorham-Stout disease (GSD)

Gorham-Stout disease (GSD) is one of the four conditions that falls under CLA. This condition typically affects bones, most commonly the ribs, skull, collar bones, and vertebrae. Also known as “vanishing bone disease”, patients’ bones tend to weaken, causing pain and fractures.

The latest on our research

We are jumpstarting our GSD program in partnership with the Lymphangiomatosis & Gorham’s Disease Alliance to accelerate research for the condition. We welcome all patients, caregivers and researchers interested in participating and spreading the word to the GSD community.