Treatment Patterns for Depression and Anxiety Among Patients with Progressive Supranuclear Palsy (PSP)

Progressive supranuclear palsy (PSP) is a rare, rapidly progressing, neurodegenerative disease that affects the brain and motor function. This study describes the treatment patterns for co-occurring mental health conditions of 80 PSP patients. 46 patients (58%) had a diagnosis (dx) of anxiety/depression/mood disorder, and among those, 18 had multiple diagnoses. 39 patients were prescribed >=1 depression/anxiety medication either before or after PSP dx. SSRIs were the most common medication prescribed, followed by benzodiazepines, and SSRIs had the most ongoing usage. This study provides new insight into how PSP patients are treated for mental health conditions before and after a PSP dx highlighting the multifaceted burden of disease among PSP patients.