Your (or your loved one’s) medical records contain clues that can lead to new treatments.
AllStripes researchers learn from patient records what would truly improve quality of life.
Using cutting-edge tech we analyze your community’s data to improve trial design and chances of success.
Your community’s de-identified records can advance multiple treatment studies.
We do the work to collect all your records, at no cost, in your secure account. Access doctors’ notes you’ve never seen.
See how your rare disease journey compares to others with your condition, and what’s helping.
We’ll send you exclusive updates on the studies you’re contributing to and how you’re driving forward research.
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), is a rare genetic mitochondrial disorder. Mitochondria are the powerhouses of our cells and when they do not work properly it can affect many different body systems. The brain, nervous system, and muscles are primarily affected in patients with MELAS. Early symptoms of MELAS include muscle weakness and pain, loss of appetite, recurrent headaches, seizures, vomiting, and stroke-like episodes. As individuals experience repeated stroke-like episodes, symptoms may progress to vision loss, movement disorders, and dementia. The heart, gastrointestinal system, kidneys, endocrine system, and skin may be affected as well.
MELAS is caused by mutations in one of several mitochondrial DNA genes. More than 80% of individuals with MELAS have mutations in a gene called MT-TL1.
Current management is aimed at treating acute stroke-like episodes, alleviating symptoms, and improving quality of life.
The latest on our research: We are jumpstarting our MELAS program to accelerate research on this condition and to ultimately improve treatment options. We welcome all patients and caregivers interested in participating and spreading the word to the MELAS community.
1. Sign up
Create your private account and review our research consent (takes about 10 minutes)
2. We get to work
We do all the behind-the-scenes work to retrieve and process your records
3. Impact research
Power multiple research projects at once by contributing your de-identified data
We believe that the only way to keep data accessible to the researchers who need it is by enabling patients to own and control their own data. Patients decide for themselves whether they want to privately and securely contribute to research, rather than having the decision made on their behalf.
We aim to make useful data accessible to all researchers who have legitimate research questions or research programs. For academic research, we offer access without charge. We take research ethics seriously, and we have policies in place to ensure that research is conducted with integrity.
We don’t like to take sides—we give all members of the community the option to get involved. Success in rare disease research takes a village and we always welcome additional collaborators who can advance and benefit from the mission.
Our primary mission is to accelerate drug development, so we prioritize generating insights specifically relevant to therapeutic research. We invest deeply in quality, security, and compliance to make this a reality.